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The 5 Critical Areas of Your Body Regulated by Your Endocannabinoid System

Balance is everything. 

From staying mentally sharp to physically healthy, your body craves the perfect balance that keeps you alive and well.

The naturally organic balance that occurs in your body is called homeostasis. And it’s your endocannabinoid system (ECS) that controls it.

Your ECS

Never heard of an endocannabinoid system? You’re not alone. And, let’s face it: “Cannabinoid” sounds a lot like “cannabis.

It’s true—The ECS was named after the cannabis plant that led to its discovery. But a lesser-known fact is that cannabinoids are not just present in the cannabis plant. Cannabinoids (phytocannabinoids) exist in a wide variety of non-cannabis, therapeutic, herbals and botanicals. And these phytocannabinoids do not have the psychoactive properties of cannabis.

And that is our mission at Emerald Health: we will introduce you to cannabinoids beyond cannabis.

The endocannabinoid system may be new to you but it’s a critical component to your body’s homeostasis. Your ECS is packed with compounds called cannabinoids. These cannabinoids influence absolutely everything that has to do with how well your body functions, from memory to sleep to emotions.

The Big 5

Your ECS influences five crucial body systems:

  • Central nervous system
  • Brain
  • Intestinal tract
  • Immune system
  • Peripheral nervous system

Let’s take a look at each of them and the role they play in your healthy lifestyle.

Central Nervous System

Your body has something called receptors that receive the important information your body transmits and helps organs, muscles and nerves act on that data.

The central nervous system [CNS] is comprised of two things: Your brain and your spinal cord. The spinal cord is the information highway – your own, personal 411 – that is the focal point of communication between your brain and your body.

The biggest difference between your CNS and other bodily systems is that it is responsible for multiple functions rather than just one isolated function. The central nervous system controls things like speaking, walking and other voluntary movements in addition to involuntary movements like breathing.

The spinal cord has cells that receive information from your endocannabinoid system which are acted upon thanks to the CB1 receptors.

There are two primary cell cannabinoid receptors: CB1 and CB2. These receptors are found throughout the body. However, certain areas concentrate one or the other receptors.

CB1 receptors are abundant in the brain. CB2 receptors are more often found on immune cells, in the gastrointestinal tract, and in the peripheral nervous system.


The brain is also part of your central nervous system … and therefore part of the CB1 receptor family … and is the organ that is your interpreter or both external and internal stimuli.

Here’s how your endocannabinoid system and your brain interact to form homeostasis. You’re hungry. Your body gives you cues to get some food because your body is sensing a nutritional deficit. Food will restore your body’s balance.

Another good example can be seen in the brain’s pleasure centers that motivate your behavior. Those centers are taking their cues from your endocannabinoid system.

Intestinal Tract

Because the ECS sends signals all over your body, you know that your intestinal tract will be a part of this too. Both the CB1 and CB2 receptors are present in your gut.

For CB1, they tend to be more present in the nerves that link your stomach to your brain.This gut-brain connection is also known as the gut-brain axis where your ECS helps coordinate the messages going back and forth.

Your endocannabinoid system can do things like …

  • Help your feeling of fullness so you don’t overeat
  • Trigger a response to inflammation, and
  • Regulate the amount of acid that’s produced in your stomach

Immune Cells

As you know, your gastrointestinal tract contains as much as 80% of your immune system. And the endocannabinoid system modulates the overall function of your immune cells.

Your immune system is actually a huge network of cells that react to CB receptors. An imbalance in your immune system can signal the start of an auto-immune disease.

Peripheral Nervous System

The peripheral nervous system is just as it sounds: On the periphery. It includes anything outside the brain and spinal cord. This means all of the nerves that branch out from your brain and spinal cord and reach muscles, organs and tissues.

The peripheral nervous system [PNS] is where the majority of the CB2 receptors can be found, most particularly in the immune cells. For example, one major role that your ECS plays in your peripheral nervous system is combating inflammation which is an immune cell response and plays a significant role in disease.

Your endocannabinoid system is present in all parts of your body helping to maintain optimum homeostasis for health and longevity.

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