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Your Endocannabinoid System, Cannabinoid Receptors and Vibrant Health


You know what it’s like to feel true balance; things in your life just naturally fall into place.


Like a house you’ve admired for years has just gone on the market, and the seller happens to be your realtor’s sister so you’re first in line. Or when you wake up feeling rejuvenated and ready for the day … even on the morning of a huge presentation at work or school.


Your body has its own organic balance that’s also known as homeostasis. That’s the role your endocannabinoid system (ECS) and receptors play.


The endocannabinoid system may be something you’ve never heard about before but it’s a critical component to your body’s homeostasis. The ECS influences everything in your body from memory to sleep to emotions.




The Accidental Discovery of the ECS


The wonders of the endocannabinoid system were discovered while researching, of all things, the marijuana plant. Scientists were studying the effects of THC – the compound in marijuana that makes you high. But through their intensive research, they discovered the Endocannabinoid System and it’s valuable role in health.


What’s more they also found that many herbs and botanicals other than the marijuana plant contain phytocannabinoids that help balance your ECS.


This system is made up of a group of compounds called cannabinoids, as well as cannabinoid receptors. Receptors are tiny sensing devices that work with your cells to help keep your body’s ideal balance. The ECS is believed to have more cellular receptor sites than any other receptor system.


The best known cannabinoid receptor sites are those found in areas called cannabinoid receptor 1 [CB1] and cannabinoid receptor 2 [CB2]. Where do they live? All through your body.


Cannabinoids bind to CB1 and CB2 receptor genes which can, in turn, change how your cells function. CB1 receptors control psycho activity, while CB2 jumps in to adjust, among other things, immune response.


CB1 and CB2 receptors have the important job of keeping our hormones and neuro hormones (the ones in your brain) in balance. They do this by either starting or stopping hormonal activity.


Cannabinoids and their receptors help regulate your…


  • Central Nervous System
  • Immune System
  • Muscular System


...All of which directly affect your health and well-being.



Retrograde Signaling


This type of signaling … getting a system or bodily function to ease up … is something the CB1 and CB2 receptors do well. Here’s an example.


Let’s say you’ve caught the flu and have started to run a fever. Your immune system will kick into high gear and go to work attacking the bug by elevating your core body temperature.


But what happens when your fever breaks? That’s retrograde signaling where your body is told to cool off because the invader has been dealt with. That happens because of your endocannabinoid system.


Here’s another example. Suppose you’re in the middle of a stressful situation. When this happens, your adrenal glands produce a lot of adrenalin. Too much adrenalin can make you feel nervous and anxious.


What cannabinoids do is attach themselves to the receptors associated with anxiety. This, in turn, tells your hormones to stop producing so much adrenalin.


The result? Your body gets back to perfect balance and your anxiety goes away.





Reference links:

Discovery of the ECS pdf provided by client